Pancreatic cancer symptoms diagnosis treatment and prevention

Reviewed by Kamran Mahmood, MD, MPH, Associate Professor of Medicine, Duke University Medical Center, Board Certified in Pulmonology & Critical Care.
Pancreatic cancer is one of the most aggressive and deadly cancers, often remaining undetected until it reaches an advanced stage. Since early symptoms are vague or non-specific, many cases go undiagnosed until the cancer has spread. The pancreas, a vital organ responsible for digestion and blood sugar regulation, can develop cancer in either its exocrine cells (which aid digestion) or endocrine cells (which produce insulin and other hormones). Early detection is challenging, making awareness of risk factors, symptoms, and screening methods crucial for improving survival rates.
Jaundice (yellowing of the skin and eyes).
Unexplained weight loss.
Digestive issues such as bloating, nausea, or greasy stools.
Persistent abdominal or back pain.
Sudden onset of diabetes or difficulty managing existing diabetes.
CT scans, MRIs, and endoscopic ultrasounds help detect tumors.
Confirms the presence of cancer cells.
Check for elevated levels of CA 19-9, a tumor marker for pancreatic cancer.
Whipple procedure or distal pancreatectomy to remove tumors.
Used to shrink tumors before surgery or target residual cancer cells afterward.
For patients with specific genetic mutations.
Focused on symptom management and quality of life.
Screening is recommended for individuals at high risk, such as those with a family history or genetic conditions.
Avoid smoking, a major risk factor.
Maintain a healthy weight and active lifestyle.
Limit alcohol consumption and manage conditions like diabetes effectively.
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